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Enhanced mortality despite control of lung infection in mice aerogenically infected with a Mycobacterium tuberculosis mce1 operon mutant

Mycobacterium tuberculosis causes a variety of host clinical outcomes. We previously showed that M. tuberculosis disrupted in an operon called mce1 proliferates unchecked in BALB/c mouse lungs. The observed outcome could be attributed either to the mutant bacterial burden or to the host immunopathol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lima, Patricia, Sidders, Ben, Morici, Lisa, Reader, Rachel, Senaratne, Ryan, Casali, Nicola, Riley, Lee W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894154/
https://ncbi.nlm.nih.gov/pubmed/17890119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2007.05.020
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