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Sirolimus enhances the magnitude and quality of viral-specific CD8(+) T cell responses to vaccinia virus vaccination in rhesus macaques
Sirolimus is a potent anti-proliferative agent used clinically to prevent renal allograft rejection. However, little is known about the effects of maintenance immunosuppressive agents on the immune response to potentially protective vaccines. Here we show that sirolimus paradoxically increases the m...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076606/ https://ncbi.nlm.nih.gov/pubmed/21342450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03407.x |
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