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A transgenic mouse for in vivo detection of endogenous labeled mRNA
Live-cell single mRNA imaging is a powerful tool, but has been restricted in higher eukaryotes to artificial cell lines and reporter genes. We describe an approach that enables live-cell imaging of single endogenous labeled mRNA molecules transcribed in primary mammalian cells and tissue. We generat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076588/ https://ncbi.nlm.nih.gov/pubmed/21240280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1551 |
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