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In vivo dynamics of RNA polymerase II transcription

We imaged transcription in living cells using a locus-specific reporter system, which allowed precise, single-cell kinetic measurements of promoter binding, initiation and elongation. Photobleaching of fluorescent RNA polymerase II revealed several kinetically distinct populations of the enzyme inte...

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Autores principales: Darzacq, Xavier, Shav-Tal, Yaron, de Turris, Valeria, Brody, Yehuda, Shenoy, Shailesh M, Phair, Robert D, Singer, Robert H
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942130/
https://ncbi.nlm.nih.gov/pubmed/17676063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1280
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