In vivo dynamics of RNA polymerase II transcription

We imaged transcription in living cells using a locus-specific reporter system, which allowed precise, single-cell kinetic measurements of promoter binding, initiation and elongation. Photobleaching of fluorescent RNA polymerase II revealed several kinetically distinct populations of the enzyme inte...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Darzacq, Xavier, Shav-Tal, Yaron, de Turris, Valeria, Brody, Yehuda, Shenoy, Shailesh M, Phair, Robert D, Singer, Robert H
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942130/
https://ncbi.nlm.nih.gov/pubmed/17676063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1280
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