Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

Breast cancer is a genetically and clinically heterogeneous disease, and the contributions of different target cells and different oncogenic mutations to this heterogeneity are not well understood. Here we report that mammary tumors induced by components of the Wnt signaling pathway contain heteroge...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Li, Yi, Welm, Bryan, Podsypanina, Katrina, Huang, Shixia, Chamorro, Mario, Zhang, Xiaomei, Rowlands, Tracey, Egeblad, Mikala, Cowin, Pam, Werb, Zena, Tan, Lee K., Rosen, Jeffrey M., Varmus, Harold E.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2003
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307657/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14668450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2136825100
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