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Inhibition of mutant p53 expression and growth of DMS-153 small cell lung carcinoma by antagonists of growth hormone-releasing hormone and bombesin

We investigated the effects of growth hormone-releasing hormone (GHRH) antagonists, JV-1-65 and JV-1-63, and bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC-3940-II on DMS-153 human small cell lung carcinoma xenografted into nude mice. Treatment with 10 μg/day JV-1-65 or RC-3940-II decreas...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kanashiro, Celia A., Schally, Andrew V., Groot, Kate, Armatis, Patricia, Bernardino, Andrea L. F., Varga, Jozsef L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307654/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2536558100
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