Cerivastatin, Genetic Variants, and the Risk of Rhabdomyolysis

OBJECTIVE: The withdrawal of cerivastatin involved an uncommon but serious adverse reaction, rhabdomyolysis. The bimodal response--rhabdomyolysis in a small proportion of users-- points to genetic factors as a potential cause. We conducted a case-control study to evaluate genetic markers for cerivas...

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Hauptverfasser: Marciante, Kristin D., Durda, Jon P., Heckbert, Susan R., Lumley, Thomas, Rice, Ken, McKnight, Barbara, Totah, Rheem A., Tamraz, Bani, Kroetz, Deanna L., Fukushima, Hisayo, Kaspera, Rüdiger, Bis, Joshua C., Glazer, Nicole L., Li, Guo, Austin, Thomas R., Taylor, Kent D., Rotter, Jerome I., Jaquish, Cashell E., Kwok, Pui-Yan, Tracy, Russell P., Psaty, Bruce M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076530/
https://ncbi.nlm.nih.gov/pubmed/21386754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328343dd7d
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