Cerivastatin, Genetic Variants, and the Risk of Rhabdomyolysis

OBJECTIVE: The withdrawal of cerivastatin involved an uncommon but serious adverse reaction, rhabdomyolysis. The bimodal response--rhabdomyolysis in a small proportion of users-- points to genetic factors as a potential cause. We conducted a case-control study to evaluate genetic markers for cerivas...

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Detalhes bibliográficos
Main Authors: Marciante, Kristin D., Durda, Jon P., Heckbert, Susan R., Lumley, Thomas, Rice, Ken, McKnight, Barbara, Totah, Rheem A., Tamraz, Bani, Kroetz, Deanna L., Fukushima, Hisayo, Kaspera, Rüdiger, Bis, Joshua C., Glazer, Nicole L., Li, Guo, Austin, Thomas R., Taylor, Kent D., Rotter, Jerome I., Jaquish, Cashell E., Kwok, Pui-Yan, Tracy, Russell P., Psaty, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076530/
https://ncbi.nlm.nih.gov/pubmed/21386754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328343dd7d
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