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Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications
FLT3 is a type III receptor tyrosine kinase. Mutations of FLT3 comprise one of the most frequently identified types of genetic alterations in acute myeloid leukemia. One-third of acute myeloid leukemia patients have mutations of this gene, and the majority of these mutations involve an internal tand...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076284/ https://ncbi.nlm.nih.gov/pubmed/21453545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-13 |
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