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Steroid Receptor Coactivator-1 Upregulates Integrin α(5) Expression to Promote Breast Cancer Cell Adhesion and Migration
Metastatic breast cancer (BC) remains a lethal disease with poorly understood molecular mechanisms. Steroid receptor coactivator 1 (SRC-1 or NCOA1) is overexpressed in a subset of BCs with poor prognosis. SRC-1 potentiates gene expression by serving as a coactivator for nuclear receptors and other t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076137/ https://ncbi.nlm.nih.gov/pubmed/21343398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3453 |
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