Signal Regulatory Protein α Negatively Regulates β(2) Integrin-Mediated Monocyte Adhesion, Transendothelial Migration and Phagocytosis

BACKGROUND: Signal regulate protein α (SIRPα) is involved in many functional aspects of monocytes. Here we investigate the role of SIRPα in regulating β(2) integrin-mediated monocyte adhesion, transendothelial migration (TEM) and phagocytosis. METHODOLOGY/PRINCIPAL FINDINGS: THP-1 monocytes/macropah...

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Detalhes bibliográficos
Main Authors: Liu, Dan-Qing, Li, Li-Min, Guo, Ya-Lan, Bai, Rui, Wang, Chen, Bian, Zhen, Zhang, Chen-Yu, Zen, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553263/
https://ncbi.nlm.nih.gov/pubmed/18820737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003291
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