A Peptide Mimetic of the Connexin43 Carboxyl-Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury

RATIONALE: Remodeling of connexin-43 (Cx43) gap junctions (GJs) is linked to ventricular arrhythmia. OBJECTIVES: A peptide mimetic of the carboxyl-terminal (CT) of Cx43, incorporating a Post-synaptic-density/Disks-large/ZO-1 (PDZ)-binding domain, reduces Cx43/ZO-1 interaction and GJ size remodeling...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: O’Quinn, Michael P., Palatinus, Joseph A., Harris, Brett S., Hewett, Kenneth W., Gourdie, Robert G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076085/
https://ncbi.nlm.nih.gov/pubmed/21273554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.235747
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia