TNF receptor 2, not TNF receptor 1 enhances mesenchymal stem cell-mediated cardiac protection following acute ischemia

BACKGROUND: Mesenchymal stem cells (MSCs) may improve myocardial function after ischemia/reperfusion (I/R) injury via paracrine effects, including the release of growth factors. Genetic modification of MSCs is an appealing method to enhance MSC paracrine action. Ablation of TNF receptor 1 (TNFR1), b...

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Bibliographic Details
Main Authors: Kelly, Megan L., Wang, Meijing, Crisostomo, Paul R., Abarbanell, Aaron M., Herrmann, Jeremy L., Weil, Brent R., Meldrum, Daniel R.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076044/
https://ncbi.nlm.nih.gov/pubmed/19953003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181cc0913
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