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Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore

The flux of solvent water coupled to the transit of ions through protein pores is considerable. The effect of this electroosmotic solvent flow on the binding of a neutral molecule [β-cyclodextrin (βCD)] to sites within the staphylococcal α-hemolysin pore was investigated. Mutant α-hemolysin pores we...

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Autori principali: Gu, Li-Qun, Cheley, Stephen, Bayley, Hagan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC307596/
https://ncbi.nlm.nih.gov/pubmed/14676320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2531778100
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