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Molecular targeting of Glioblastoma – how do you hit a moving target?

Cancer is a molecularly complex, genomically unstable disease. Selection for drug resistance mutations, activation of feedback loops and upregulation of cross-talk pathways provide escape routes by which cancer cells maintain signal flux through critical downstream effectors to promote therapeutic r...

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Bibliografski detalji
Glavni autori: Cloughesy, Timothy F., Mischel, Paul S.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075730/
https://ncbi.nlm.nih.gov/pubmed/21208902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2268
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