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Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor
Selective therapeutics for nuclear receptors would revolutionize treatment for endocrine disease. Specific control of nuclear receptor activity is challenging because the internal cavities that bind hormones can be virtually identical. Only one highly selective hormone analog is known for the thyroi...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307572/ https://ncbi.nlm.nih.gov/pubmed/14673100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2136689100 |
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