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Differential Temporal and Spatial Regulation of Somatostatin Receptor Phosphorylation and Dephosphorylation

The G(i)-coupled somatostatin 2A receptor (sst2A) mediates many of the neuromodulatory and neuroendocrine actions of somatostatin (SS) and is targeted by the SS analogs used to treat neuroendocrine tumors. As for other G protein-coupled receptors, agonists stimulate sst2A receptor phosphorylation on...

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Autori principali: Ghosh, Madhumita, Schonbrunn, Agnes
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075702/
https://ncbi.nlm.nih.gov/pubmed/21343287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215723
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