Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization: LINK BETWEEN THE METABOLIC AND INNATE IMMUNE ACTIVITY OF FULL-LENGTH ADIPONECTIN

The anti-inflammatory effects of globular adiponectin (gAcrp) are mediated by IL-10/heme oxygenase 1 (HO-1)-dependent pathways. Although full-length (flAcrp) adiponectin also suppresses LPS-induced pro-inflammatory signaling, its signaling mechanisms are not yet understood. The aim of this study was...

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Detalhes bibliográficos
Main Authors: Mandal, Palash, Pratt, Brian T., Barnes, Mark, McMullen, Megan R., Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075692/
https://ncbi.nlm.nih.gov/pubmed/21357416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204644
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