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In Glycine and GABA(A) Channels, Different Subunits Contribute Asymmetrically to Channel Conductance via Residues in the Extracellular Domain

Single-channel conductance in Cys-loop channels is controlled by the nature of the amino acids in the narrowest parts of the ion conduction pathway, namely the second transmembrane domain (M2) and the intracellular helix. In cationic channels, such as Torpedo ACh nicotinic receptors, conductance is...

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Detalhes bibliográficos
Main Authors: Moroni, Mirko, Meyer, James O., Lahmann, Carolina, Sivilotti, Lucia G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075687/
https://ncbi.nlm.nih.gov/pubmed/21343294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204610
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