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G Protein-coupled Receptor Signaling via Src Kinase Induces Endogenous Human Transient Receptor Potential Vanilloid Type 6 (TRPV6) Channel Activation

Ca(2+) homeostasis plays a critical role in a variety of cellular processes. We showed previously that stimulation of the prostate-specific G protein-coupled receptor (PSGR) enhances cytosolic Ca(2+) and inhibits proliferation of prostate cells. Here, we analyzed the signaling mechanisms underlying...

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Detalhes bibliográficos
Main Authors: Spehr, Jennifer, Gelis, Lian, Osterloh, Markus, Oberland, Sonja, Hatt, Hanns, Spehr, Marc, Neuhaus, Eva M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075665/
https://ncbi.nlm.nih.gov/pubmed/21349844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183525
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