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Identification of New Batrachotoxin-sensing Residues in Segment IIIS6 of the Sodium Channel
Ion permeation through voltage-gated sodium channels is modulated by various drugs and toxins. The atomistic mechanisms of action of many toxins are poorly understood. A steroidal alkaloid batrachotoxin (BTX) causes persistent channel activation by inhibiting inactivation and shifting the voltage de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075662/ https://ncbi.nlm.nih.gov/pubmed/21303907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208496 |
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