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Fibrillin-1 genetic deficiency leads to pathological aging of arteries in mice
Fibrillin-1, the major component of extracellular microfibrils that associate with insoluble elastin in elastic fibers, is mainly synthesized during development and postnatal growth and is believed to guide elastogenesis. Mutations in the fibrillin-1 gene cause Marfan syndrome, a multisystem disorde...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075583/ https://ncbi.nlm.nih.gov/pubmed/21432852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2840 |
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