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The Structural Biology of Toll-Like Receptors

The membrane-bound Toll-like receptors (TLRs) trigger innate immune responses following recognition of a wide variety of pathogen-derived compounds. Despite the wide range of ligands recognized by TLRs, the receptors share a common structural framework in their extracellular, ligand-binding domains....

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Detalhes bibliográficos
Main Authors: Botos, Istvan, Segal, David M., Davies, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075535/
https://ncbi.nlm.nih.gov/pubmed/21481769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.02.004
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