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Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling

Multiple signaling molecules, including Fibroblast Growth Factor (FGF) and Wnt, induce two patches of ectoderm on either side of the hindbrain to form the progenitor cell population for the inner ear, or otic placode. Here we report that in Spry1, Spry2 compound mutant embryos (Spry1(−/−); Spry2(−/−...

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Detalhes bibliográficos
Main Authors: Mahoney Rogers, Amanda A., Zhang, Jian, Shim, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075364/
https://ncbi.nlm.nih.gov/pubmed/21362415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.02.022
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