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Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode
The inner ear derives from a patch of ectoderm defined by expression of the transcription factor Pax2. We recently showed this Pax2(+) ectoderm gives rise not only to the otic placode but also to surrounding cranial epidermis, and that Wnt signaling mediates this placode-epidermis fate decision. We...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575054/ https://ncbi.nlm.nih.gov/pubmed/18495817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.017905 |
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