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Characterizing the existing and potential structural space of proteins by large-scale multiple loop permutations
Worldwide structural genomics projects are increasing structure coverage of sequence space but have not significantly expanded the protein structure space itself (i.e. number of unique structural folds) since 2007. Discovering new structural folds experimentally by directed evolution and random reco...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075335/ https://ncbi.nlm.nih.gov/pubmed/21376059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.056 |
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