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Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA
T cells transformed by Herpesvirus saimiri express seven viral U-rich noncoding RNAs of unknown function called HSURs. We noted that conserved sequences in HSURs 1 and 2 constitute potential binding sites for three host-cell microRNAs (miRNAs). Coimmunoprecipitation experiments confirmed that HSURs...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075239/ https://ncbi.nlm.nih.gov/pubmed/20558719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1187197 |
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