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Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

T cells transformed by Herpesvirus saimiri express seven viral U-rich noncoding RNAs of unknown function called HSURs. We noted that conserved sequences in HSURs 1 and 2 constitute potential binding sites for three host-cell microRNAs (miRNAs). Coimmunoprecipitation experiments confirmed that HSURs...

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Bibliografiset tiedot
Päätekijät: Cazalla, Demián, Yario, Therese, Steitz, Joan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075239/
https://ncbi.nlm.nih.gov/pubmed/20558719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1187197
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