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High doses of vitamin E improve mitochondrial dysfunction in rat hippocampus and frontal cortex upon aging

Rat aging from 4 to 12 mo was accompanied by hippocampus and frontal cortex mitochondrial dysfunction, with decreases of 23 to 53% in tissue and mitochondrial respiration and in the activities of complexes I and IV and of mitochondrial nitric oxide synthase (mtNOS) (P < 0.02). In aged rats, the t...

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Detalhes bibliográficos
Main Authors: Navarro, Ana, Bandez, Manuel J., Lopez-Cepero, Jose M., Gómez, Carmen, Boveris, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075077/
https://ncbi.nlm.nih.gov/pubmed/21106913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00525.2010
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