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Apolipoprotein-E forms dimers in human frontal cortex and hippocampus
BACKGROUND: Apolipoprotein-E (apoE) plays important roles in neurobiology and the apoE4 isoform increases risk for Alzheimer's disease (AD). ApoE3 and apoE2 are known to form disulphide-linked dimers in plasma and cerebrospinal fluid whereas apoE4 cannot form these dimers as it lacks a cysteine...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837047/ https://ncbi.nlm.nih.gov/pubmed/20170526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-23 |
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