Stereodifferentiation--the effect of P chirality of oligo(nucleoside phosphorothioates) on the activity of bacterial RNase H.

P stereoregular phosphorothioate analogs of pentadecamer 5'-d(AGATGTTTGAGCTCT)-3' were synthesized by the oxathiaphospholane method. Their diastereomeric purity was assigned by means of enzymatic degradation with nuclease P1 and, independently, with snake venom phosphodiesterase. DNA-RNA hybrids for...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Koziolkiewicz, M, Krakowiak, A, Kwinkowski, M, Boczkowska, M, Stec, W J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 1995
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8559657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.24.5000
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