A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy

Graves' ophthalmopathy (GO) is characterized by expanded volume of the orbital tissues associated with elevated serum levels of TSH receptor (TSHR) autoantibodies. Because previous studies have demonstrated evidence of adipogenesis within the GO orbit, we sought to determine whether M22, a huma...

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Bibliografiska uppgifter
Huvudupphovsmän: Kumar, Seema, Nadeem, Sarah, Stan, Marius N, Coenen, Michael, Bahn, Rebecca S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Endocrinology 2011
Ämnen:
Regular Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074639/
https://ncbi.nlm.nih.gov/pubmed/21321093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-11-0006
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