Co-activation of AKT and β-catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors

Obesity is a risk factor for development of certain cancers but the basis for this risk is unclear. In this study, we developed a novel mouse model that demonstrates directly how lipogenic phenotypes commonly associated with diet induced-metabolic syndromes can influence hepatic cancer development....

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Autores principales: Stauffer, Jimmy K., Scarzello, Anthony J., Andersen, Jesper B., DeKluyver, Rachel L., Back, Timothy C., Weiss, Jonathan M., Thorgeirsson, Snorri S., Wiltrout, Robert H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074499/
https://ncbi.nlm.nih.gov/pubmed/21324921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2705
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