LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours

OBJECTIVES: The relative contributions of inflammatory signalling and sequential oncogenic dysregulation driving liver cancer pathogenesis remain incompletely understood. Lymphotoxin-β receptor (LTβR) signalling is critically involved in hepatitis and liver tumorigenesis. Therefore, we explored the...

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Foilsithe in:Gut
Main Authors: Scarzello, Anthony J, Jiang, Qun, Back, Timothy, Dang, Hien, Hodge, Deborah, Hanson, Charlotte, Subleski, Jeffrey, Weiss, Jonathan M, Stauffer, Jimmy K, Chaisaingmongkol, Jitti, Rabibhadana, Siritida, Ruchirawat, Mathuros, Ortaldo, John, Wang, Xin Wei, Norris, Paula S, Ware, Carl F, Wiltrout, Robert H
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2016
Ábhair:
Hepatology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036232/
https://ncbi.nlm.nih.gov/pubmed/26206664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308810
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