Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling

In a genetic screen we isolated mutations in CG10260, which encodes a phosphatidylinositol 4-kinase (PI4KIIIalpha), and found that PI4KIIIalpha is required for Hippo signaling in Drosophila ovarian follicle cells. PI4KIIIalpha mutations in the posterior follicle cells lead to oocyte polarization def...

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Hlavní autoři: Yan, Yan, Denef, Natalie, Tang, Charm, Schüpbach, Trudi
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074446/
https://ncbi.nlm.nih.gov/pubmed/21429988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.059279
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