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Characterization of plasma membrane bound inorganic pyrophosphatase from Leishmania donovani promastigotes and amastigotes

BACKGROUND: Currently, a major problem in the management of visceral leishmaniasis or kala-azar, especially in the Indian subcontinent, is the growing unresponsiveness to conventional antimonial therapy. Membrane bound pyrophophatase (PPases) do not exist in plasma membrane from mammals. Thus, H(+)-...

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Bibliographische Detailangaben
Hauptverfasser: Sen, SS, Bhuyan, NR, Bera, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Makerere Medical School 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074396/
https://ncbi.nlm.nih.gov/pubmed/21503171
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