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Androgen-dependent hypertension is mediated by 20-HETE-induced vascular dysfunction: Role of IkappaB kinase

Increased vascular synthesis of 20-HETE is associated with increased vascular contraction, endothelial dysfunction and endothelial activation; all are believed to account for 20-HETE pro-hypertensive properties. We previously demonstrated that the 20-HETE-dependent inhibition of NO production is med...

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Bibliografiske detaljer
Main Authors: Wu, Cheng-Chia, Cheng, Jennifer, Zhang, Frank Fan, Gotlinger, Katherine H., Kelkar, Mukul, Zhang, Yilun, Jat, Jawahar L., Falck, John R., Schwartzman, Michal L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074296/
https://ncbi.nlm.nih.gov/pubmed/21321301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.161570
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