Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A

In coeliac disease, the intake of dietary gluten induces small-bowel mucosal damage and the production of immunoglobulin (Ig)A class autoantibodies against transglutaminase 2 (TG2). We examined the effect of coeliac patient IgA on the apical-to-basal passage of gluten-derived gliadin peptides p31–43...

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Autori principali: Rauhavirta, T, Qiao, S-W, Jiang, Z, Myrsky, E, Loponen, J, Korponay-Szabó, I R, Salovaara, H, Garcia-Horsman, J A, Venäläinen, J, Männistö, P T, Collighan, R, Mongeot, A, Griffin, M, Mäki, M, Kaukinen, K, Lindfors, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
Soggetti:
Translational Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074225/
https://ncbi.nlm.nih.gov/pubmed/21235541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04317.x
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