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Vitamin D Receptor Ligands, Adenomatous Polyposis Coli, and the Vitamin D Receptor FokI Polymorphism Collectively Modulate β-Catenin Activity in Colon Cancer Cells
The activity of β-catenin, commonly dysregulated in human colon cancers, is inhibited by the vitamin D receptor (VDR), and this mechanism is postulated to explain the putative anti-cancer activity of vitamin D metabolites in the colon. We investigated the effect of a common FokI restriction site pol...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074190/ https://ncbi.nlm.nih.gov/pubmed/20043299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20603 |
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