Somatic coding mutations in human induced pluripotent stem cells

Defined transcription factors can induce epigenetic reprogramming of adult mammalian cells into induced pluripotent stem cells. Although DNA factors are integrated during some reprogramming methods, it is unknown whether the genome remains unchanged at the single nucleotide level. Here we show that...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gore, Athurva, Li, Zhe, Fung, Ho-Lim, Young, Jessica, Agarwal, Suneet, Antosiewicz-Bourget, Jessica, Canto, Isabel, Giorgetti, Alessandra, Israel, Mason, Kiskinis, Evangelos, Lee, Je-Hyuk, Loh, Yuin-Han, Manos, Philip D., Montserrat, Nuria, Panopoulos, Athanasia D., Ruiz, Sergio, Wilbert, Melissa, Yu, Junying, Kirkness, Ewen F., Belmonte, Juan Carlos Izpisua, Rossi, Derrick J., Thomson, James, Eggan, Kevin, Daley, George Q., Goldstein, Lawrence S.B., Zhang, Kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074107/
https://ncbi.nlm.nih.gov/pubmed/21368825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09805
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi