Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming

Recent studies indicate that human induced pluripotent stem cells (hiPSCs) contain genomic structural variations and point mutations in coding regions. However, these studies have focused on fibroblast-derived hiPSCs, and it is currently unknown whether the use of alternative somatic cell sources wi...

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Détails bibliographiques
Auteurs principaux: Ruiz, Sergio, Gore, Athurva, Li, Zhe, Panopoulos, Athanasia D., Montserrat, Nuria, Fung, Ho-Lim, Giorgetti, Alessandra, Bilic, Josipa, Batchelder, Erika M., Zaehres, Holm, Schöler, Hans R., Zhang, Kun, Belmonte, Juan Carlos Izpisua
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856317/
https://ncbi.nlm.nih.gov/pubmed/23340422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2381
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