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Hedgehog Activity, Epithelial-Mesenchymal Transitions, and Biliary Dysmorphogenesis in Biliary Atresia

BACKGROUND: Biliary Atresia (BA) is notable for marked ductular reaction and rapid development of fibrosis. Activation of the Hedgehog (Hh) pathway promotes the expansion of populations of immature epithelial cells that co-express mesenchymal markers and may be pro-fibrogenic. We examined the hypoth...

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Detalhes bibliográficos
Main Authors: Omenetti, Alessia, Bass, Lee M, Anders, Robert A., Clemente, Maria G, Francis, Heather, Guy, Cinthya D, McCall, Shannon, Choi, Steve S, Alpini, Gianfranco, Schwarz, Kathleen B, Diehl, Anna Mae, Whitington, Peter F
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074103/
https://ncbi.nlm.nih.gov/pubmed/21480329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24156
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