Hedgehog Activity, Epithelial-Mesenchymal Transitions, and Biliary Dysmorphogenesis in Biliary Atresia

BACKGROUND: Biliary Atresia (BA) is notable for marked ductular reaction and rapid development of fibrosis. Activation of the Hedgehog (Hh) pathway promotes the expansion of populations of immature epithelial cells that co-express mesenchymal markers and may be pro-fibrogenic. We examined the hypoth...

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Autors principals: Omenetti, Alessia, Bass, Lee M, Anders, Robert A., Clemente, Maria G, Francis, Heather, Guy, Cinthya D, McCall, Shannon, Choi, Steve S, Alpini, Gianfranco, Schwarz, Kathleen B, Diehl, Anna Mae, Whitington, Peter F
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074103/
https://ncbi.nlm.nih.gov/pubmed/21480329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24156
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