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Role for Tumor Necrosis Factor-alpha in JC Virus Reactivation and Progressive Multifocal Leukoencephalopathy
JCV causes the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML). After primary infection, JCV persists in a latent state, where viral protein expression and replication are not detectable. NF-κB and C/EBPβ regulate the JCV promoter via a control element, κB, suggesting proi...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074035/ https://ncbi.nlm.nih.gov/pubmed/21185609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.11.013 |
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