Role for Tumor Necrosis Factor-alpha in JC Virus Reactivation and Progressive Multifocal Leukoencephalopathy

JCV causes the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML). After primary infection, JCV persists in a latent state, where viral protein expression and replication are not detectable. NF-κB and C/EBPβ regulate the JCV promoter via a control element, κB, suggesting proi...

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Main Authors: Wollebo, Hassen S., Safak, Mahmut, Valle, Luis Del, Khalili, Kamel, White, Martyn K.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074035/
https://ncbi.nlm.nih.gov/pubmed/21185609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.11.013
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