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Splice Site Mutations in the ATP7A Gene

Menkes disease (MD) is caused by mutations in the ATP7A gene. We describe 33 novel splice site mutations detected in patients with MD or the milder phenotypic form, Occipital Horn Syndrome. We review these 33 mutations together with 28 previously published splice site mutations. We investigate 12 mu...

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Detalhes bibliográficos
Main Authors: Skjørringe, Tina, Tümer, Zeynep, Møller, Lisbeth Birk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073976/
https://ncbi.nlm.nih.gov/pubmed/21494555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018599
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