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Catalytic site-specific cleavage of a DNA-target by an oligonucleotide carrying bleomycin A5.
Oligonucleotide reagents have been created which are capable of catalytic site-specific cleavage of DNA-targets. The oligonucleotide reagent Blm-R-pd(CCAAACA) bearing the bleomycin A5 (Blm-RH) residue was used to degrade the DNA-target pd(TGTTTGGCGAAGGA). It has been shown that at equimolar reagent:...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1995
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307396/ https://ncbi.nlm.nih.gov/pubmed/7501462 |
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