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Catalytic site-specific cleavage of a DNA-target by an oligonucleotide carrying bleomycin A5.

Oligonucleotide reagents have been created which are capable of catalytic site-specific cleavage of DNA-targets. The oligonucleotide reagent Blm-R-pd(CCAAACA) bearing the bleomycin A5 (Blm-RH) residue was used to degrade the DNA-target pd(TGTTTGGCGAAGGA). It has been shown that at equimolar reagent:...

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Pubblicato in:Nucleic Acids Res
Autori principali: Sergeyev, D S, Godovikova, T S, Zarytova, V F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1995
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4400
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