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Insights from Modeling the 3D Structure of New Delhi Metallo-β-Lactamse and Its Binding Interactions with Antibiotic Drugs

New Delhi metallo-beta-lactamase (NDM-1) is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotic drugs. This is because it can inactivate most beta-lactam antibiotic drugs by hydrolyzing them. For in-depth understanding of the hydrolysis mechanism, the three-dimensional...

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Detalhes bibliográficos
Main Authors: Wang, Jing-Fang, Chou, Kuo-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073942/
https://ncbi.nlm.nih.gov/pubmed/21494599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018414
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