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Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway

BACKGROUND: To explore the effects of Osthole on the proliferation, cell cycle and apoptosis of human lung cancer A549 cells. METHODS: Human lung cancer A549 cells were treated with Osthole at different concentrations. Cell proliferation was measured using the MTT assay. Cell cycle was evaluated usi...

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Detalhes bibliográficos
Main Authors: Xu, Xiaoman, Zhang, Yi, Qu, Dan, Jiang, Tingshu, Li, Shengqi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073874/
https://ncbi.nlm.nih.gov/pubmed/21447176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-33
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