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Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent.

Antisense oligodeoxynucleotides can selectively inhibit the expression of individual genes and thus have potential applications in anticancer and antiviral therapy. A critical prerequisite to their use as therapeutic agents is the understanding of their non-specific interactions with biological stru...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Benimetskaya, L, Tonkinson, J L, Koziolkiewicz, M, Karwowski, B, Guga, P, Zeltser, R, Stec, W, Stein, C A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1995
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4239
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